Web servers or programs in other languages in charge

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Programs in virtually any programming language can be in charge.  There are interface routines available in Visual Basic, Delphi, Visual C++, Oracle, and Java as developed by Erwin Kalvelagen at GAMS Development Corp and distributed through http://www.gams.com/~erwin/interface/interface.html.

There are also web server based implementations including

GAMS-X developed by Tom Rutherford and Colin Starkweather which is described and available at http://www.gams-x.com/.
GAMSsm developed by Tom Rutherford which is described and available at http://www.mpsge.org/gamssm/index.html.
KESTREL developed by the NEOS group at http://www-neos.mcs.anl.gov/neos/.

These are all quite technical and those wishing go further are urged to consult the descriptions above along with technical language and operating system documents.